Rash in crease of leg and groin

Rash in crease of leg and groin

What is intertrigo?

Intertrigo is a rash that usually affects the folds of the skin, where the skin rubs together or where it is often moist. This rubbing can cause a breakdown in the top layers of the skin, causing inflammation and a rash. The breakdown of skin makes it easier for bacteria or fungus to develop in this area. It can make the rash worse.

Intertrigo is most common in people who are overweight or who have diabetes. People who have splints, braces, or artificial limbs are also more likely to develop this rash.

Symptoms of intertrigo

Symptoms of intertrigo include a red or reddish-brown rash that can appear anywhere skin rubs together or traps wetness. This rash may burn or itch. The most common areas include:

  • Between toes
  • In the armpits
  • In the groin area
  • On the underside of the belly or breasts
  • In the crease of the neck

Intertrigo can also affect the skin between the buttocks. The affected skin will often be very raw and may itch or ooze. In severe cases, intertrigo may cause a foul odor, and the skin may crack and bleed.

What causes intertrigo?

Skin folds sitting together and rubbing together causes intertrigo. This skin-on-skin friction creates a warm, moist environment. This environment invites an overgrowth of yeast, fungus, and bacteria. Intertrigo is not contagious. You cannot catch it from or pass it to another person.

How is intertrigo diagnosed?

The best way to know for sure is to ask your doctor. Your doctor will be able to tell if you have intertrigo by looking at your rash. No special tests are needed but your doctor may take a sample to determine what type of bacteria or fungus may be present.

Can intertrigo be prevented or avoided?

You can help prevent intertrigo by doing these things:

  • Keep skin cool and dry.
  • Do not wear tight shoes or clothing. Wear a bra that has good support.
  • Wear clothes made with absorbent fabrics, such as cotton. Avoid nylon or other synthetic (manmade) fibers.
  • If you are overweight, try to lose weight.
  • After exercising, shower and dry off completely. Use a hair dryer with a cool setting to dry areas that can trap wetness, such as under your arms or breasts.

Intertrigo treatment

For mild cases, your doctor will tell you to keep the affected area of your skin dry and exposed to air. Your doctor may also want to prescribe a topical steroid cream. For certain cases, your doctor may prescribe an antibiotic or antifungal cream. There are also antifungal powders that may help dry the skin. Talk to your doctor about which treatment is right for you.

Living with intertrigo

Intertrigo may come and go. If you know that you are predisposed to getting intertrigo, take precautions. Before physical activity, treat the area with deodorant or with petroleum jelly. Do what you can to keep skin folds dry.

Questions to ask your doctor

  • What is the best way to keep from getting intertrigo again?
  • Do I need to make any changes to my lifestyle?
  • Do I need to use a cream or ointment?
  • What side effects could I have from my medicine?
  • Do I need to take an antibiotic?
  • Is there anything I can do on my own to help myself get better?

Resources

Rash in crease of leg and groin

Copyright © American Academy of Family Physicians

This information provides a general overview and may not apply to everyone. Talk to your family doctor to find out if this information applies to you and to get more information on this subject.

Author: Hon A/Prof Amanda Oakley, Dermatologist, Hamilton, New Zealand, 1998. Revised and updated August 2015. Updated by Janet Dennis, November 2018. Technical Editor: Mary Elaine Luther, Medical Student, Ross University, Barbados. DermNet Editor in Chief: Adjunct A/Prof Amanda Oakley, Dermatologist, Hamilton, New Zealand. Copy edited by Gus Mitchell. January 2020.


What is intertrigo?

Intertrigo describes a rash in the flexures, such as behind the ears, in the folds of the neck, under the arms, under a protruding abdomen, in the groin, between the buttocks, in the finger webs, or in the toe spaces. Although intertrigo can affect only one skin fold, intertrigo commonly involves multiple sites. Intertrigo is a sign of inflammation or infection.

Who gets intertrigo?

Intertrigo can affect males or females of any age. Intertrigo is particularly common in people who are overweight or obese (see metabolic syndrome).

Other contributing factors are:

  • Genetic tendency to skin disease
  • Hyperhidrosis (excessive sweating)
  • Age
  • Diabetes
  • Smoking
  • Alcohol.

In infants, napkin dermatitis is a type of intertrigo that primarily occurs due to skin exposure to sweat, urine, and faeces in the diaper area.

Toe-web intertrigo is associated with closed-toe or tight-fitting shoes. Lymphoedema is also a cause for toe-web intertrigo.

What are the clinical features of intertrigo?

Intertrigo can be acute (recent onset), relapsing (recurrent), or chronic (present for more than six weeks). The exact appearance and behaviour depend on the underlying cause(s).

The skin affected by intertrigo is inflamed, reddened, and uncomfortable. The affected skin can become moist and macerated, leading to fissuring (cracks) and peeling.

Intertrigo with secondary bacterial infection (eg, pseudomonas) can cause a foul odour.

What causes intertrigo?

Intertrigo is due to genetic and environmental factors.

  • Flexural skin has a relatively high surface temperature.
  • Moisture from insensible water loss and sweating cannot evaporate due to occlusion.
  • Friction from the movement of adjacent skin results in chafing.
  • Intertrigo occurs more easily in environments that are hot and humid.
  • Diabetes, alcohol, and smoking increase the likelihood of intertrigo, especially the infectious form.

The microbiome (microorganisms normally resident on the skin) on flexural skin includes Corynebacterium, other bacteria, and yeasts. Microbiome overgrowth in warm moist environments can cause intertrigo.

Intertrigo is classified into infectious and inflammatory origins, but they often overlap.

  • Infections tend to be unilateral and asymmetrical.
  • Atopic dermatitis is usually bilateral and symmetrical, affecting the flexures of the neck, knees and elbows.
  • Other inflammatory disorders also tend to be symmetrical affecting the armpits, groins, under the breasts, and the abdominal folds.

Infections causing intertrigo

Thrush: Candida albicans

  • Characterised by its rapid development
  • Itchy, moist, peeling, red and white skin
  • Small superficial papules and pustules
Candida albicans

Erythrasma: Corynebacterium minutissimum

  • Persistent brown patches
  • Minimal scale
  • Asymptomatic (painless and non-itchy)
Erythrasma

Tinea: Trichophyton rubrum + T. interdigitale

  • Tinea cruris (groin) and athletes foot (between toes)
  • Slowly spreads over weeks to months
  • Irregular annular plaques
  • Peeling, scaling
Tinea cruris

Impetigo: Staphylococcus aureus and Streptococcus pyogenes

  • Rapid development
  • Moist blisters and crusts on a red base
  • Contagious, so other family members may also be affected
Impetigo

Boils: Staphylococcus aureus

  • Rapid development
  • Very painful follicular papules and nodules
  • Central pustule or abscess
Boil

Rash in crease of leg and groin

Folliculitis: Staphylococcus aureus

  • Acute or chronic
  • Superficial tender red papules
  • Pustules centred on hair follicles
  • Can be provoked by shaving, waxing, epilation.
Folliculitis

Skin inflammations causing intertrigo

Flexural psoriasis

  • Well-defined, smooth or shiny red patches
  • Very persistent
  • Common in submammary and groin creases
  • Symmetrical involvement
  • May fissure (crack) in the crease
  • Red patches on other sites are scaly
Flexural psoriasis

Seborrhoeic dermatitis

  • Ill-defined salmon-pink thin patches
  • Common in axilla and groin creases
  • Fluctuates in severity
  • May be asymmetrical
  • Often unnoticed
  • Red patches on the face and scalp tend to be flaky.
Seborrhoeic dermatitis

Atopic dermatitis

  • First occurs in infancy
  • Common in elbow and knee creases
  • Characterised by flares
  • Very itchy
  • Acute eczema is red, blistered, swollen
  • Chronic eczema is dry, thickened, lined (lichenified).
Atopic dermatitis

Contact irritant dermatitis

  • Acute, relapsing or chronic

Irritants include:

  • Body fluids: sweat, urine
  • Friction due to movement and clothing
  • Dryness due to antiperspirant
  • Soap
  • Excessive washing.
Irritant contact dermatitis

Contact allergic dermatitis

  • Acute or relapsing
  • The allergen may be:
    • Fragrance, preservative or medicament in deodorant, wet-wipe or other product
    • Component of underwear (rubber in elastic, nickel in bra wire).
Allergic contact dermatitis

Rash in crease of leg and groin

Hidradenitis suppurativa

  • Chronic disorder
  • Boil-like follicular papules and nodules
  • Discharging sinuses and scars
Hidradenitis suppurativa 

Hailey-Hailey disease

  • Intermittent painful shallow blisters that quickly break down
  • Rare inherited condition
  • Often starts age 20–40 years
  • Most troublesome during summer months
Hailey-Hailey disease

Granular parakeratosis

  • Red-brown scaly rash
  • Can be itchy
  • Rare
  • A biopsy is essential for diagnosis.
Granular parakeratosis

Fox-Fordyce disease

  • Dome-shaped follicular papules in armpits
  • Often persistent
  • Asymptomatic or itchy
  • Reduced sweating
  • Excoriations and lichenification eventually occur as a result of scratching.
Fox-Fordyce disease

Toe-web intertrigo

  • Common in persons wearing tight-fitting shoes
  • Pseudomonas aeruginosa is the most common organism
  • Mild toe-web intertrigo presents with erythema and scaling (athlete's foot)
  • Chronic intertrigo (longer than six months) causes burning pain, exudation, maceration, and inability to move the toes
  • A serious complication is cellulitis, often spreading to ankles and knees.
Toe-web intertrigo

What investigations should be done?

Investigations may be necessary to determine the cause of intertrigo.

  • A swab for microscopy and culture of bacteria (microbiology)
  • A scraping for microscopy and culture of fungi (mycology)
  • A skin biopsy may be performed for histopathology if the skin condition is unusual or fails to respond to treatment.

What is the treatment for intertrigo?

  • Treatment depends on the underlying cause if identified, and on which micro-organisms are present in the rash. Combinations are common.
  • Zinc oxide paste can be used for napkin dermatitis or incontinence-associated irritant contact dermatitis.
  • Physical exertion should be followed by bathing and completely drying skin flexures. A hairdryer on cool setting is an effective approach for drying underarms and breasts.
  • Sweating can be reduced with an antiperspirant cream or powder.
  • Bacterial infection may be treated with topical antibiotics such as fusidic acid cream, mupirocin ointment, or oral antibiotics such as flucloxacillin and erythromycin.
  • Yeasts and fungi may be treated with topical antifungals such as clotrimazole and terbinafine cream or oral antifungal agents such as itraconazole or terbinafine.
  • Inflammatory skin diseases are often treated with low potency topical steroid creams such as hydrocortisone. More potent steroids are best avoided in the flexures because they can cause skin thinning, resulting in stretch marks (striae atrophicae) and rarely, ulcers. Calcineurin inhibitors such as tacrolimus ointment or pimecrolimus cream are also effective in skin folds.

How do I get rid of a rash between my groin and thigh?

If you have a rash:.
Apply cool compresses to soothe irritation and reduce itching. Oatmeal baths help, too..
Use OTC hydrocortisone creams or antihistamines (with your doctor's approval) to help relieve itching..
Avoid anything you think may be irritating your skin..

What does a fungal infection look like in the groin?

Red, slightly scaly skin then develops in the groin, usually with a definite edge or border. Both sides are commonly affected. The rash often spreads a short way down the inside of both thighs.

What does a rash on your inner thighs mean?

Summary. A rash on the inner thigh or groin area is an uncomfortable experience. Possible causes include eczema, contact dermatitis, chafing, heat rash, hidradenitis suppurativa, jock itch, pityriasis rosea, razor burn, swimmer's itch, and STIs. The symptoms and treatment options vary by cause.

How do you treat a rash in the groin area?

Treatment.
Apply an over-the-counter (OTC) antifungal cream, powder, or spray to the affected area..
Wash the affected area thoroughly with soap and warm water..
Dry the affected area thoroughly after bathing and exercise..
Change clothes and undergarments every day..
Wear loose cotton clothing..