Review of Treatment and Prognosis of Stage IVB Cervical CarcinomaTomoka Usami et al. Int J Gynecol Cancer. 2016 Sep. Show
AbstractObjectives: In most patients, stage IVB cervical cancer is incurable, and the outcomes are poor. There is significant individual variation in patients with stage IVB cervical cancer, in whom standard treatment has not been well defined. This study aims to review the outcomes and discuss treatment strategies in patients with stage IVB cervical cancer. Methods: From January 1, 1992, to December 31, 2011, we retrospectively reviewed the data of patients with stage IVB cervical cancer who were given a diagnosis at the Department of Gynecology of the Cancer Institute Hospital. Results: A total of 111 patients were enrolled. At the time of analysis, the median overall survival (OS) was 16.6 months (range, 0.2-120.9 months), and the 5-year OS rate was 20.2%. The 5-year OS rate was 59.4% for those with only para-aortic lymph node metastases; 24.8% for those with lymphogenous metastases, excluding those with only para-aortic lymph node metastases; 6.1% for those with hematogenous metastases; and 0% for those with disseminated metastases. The OS in patients with lymphogenous metastases was better compared with that of those with either hematogenous or disseminated metastases (P < 0.0001). In multivariate analysis, the performance status, site of metastases (only lymph node or other metastases), and local stage were all independent prognostic factors. Conclusions: We determined performance status, site of metastases (only lymph node or other metastases), and local stage as independent prognostic factors in patients with stage IVB cervical cancer. Regarding treatment, we confirmed that the effectiveness of chemotherapy was also of significance. Similar articles
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Can cervical cancer be cured in its fourth stage?Stage 4 cervical cancer is not curable in many cases. However, nearly 17 in 100 women will beat stage 4 cervical cancer. It is crucial to seek expert gynecologic oncology support in a high-quality healthcare system to determine the best course of action for you and your family.
How long can you live after cervical cancer treatment?5-year relative survival rates for cervical cancer. Does Chemo help Stage 4 cancer?Stage 4 cancer is challenging to treat, but treatment options may help control the cancer and improve pain, other symptoms and quality of life. Systemic drug treatments, such as targeted therapy or chemotherapy, are common for stage 4 cancers.
What is the best treatment for stage 4 cervical cancer?Stage 4 means the cancer has spread to the bladder or back passage (rectum) or further away. The main treatments are surgery, radiotherapy, chemotherapy or a combination of these treatments. Or you might have treatment to control symptoms.
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