What is the difference between vitamin d3 and vitamin d2

What is the difference between vitamin d3 and vitamin d2

Vitamin D or the sunshine vitamin as it is known is important for immune system, bone health and the health of our teeth. It is found in supplements in two different forms; one form is vitamin D3 (cholecalciferol) and the other is vitamin D2 (ergocalciferol). People often want to know the differences between D2 and D3. So, which one is best?

D3 is the sunshine vitamin, D2 isn’t

It’s vitamin D3 that is found in the skin, after sunshine converts cholesterol into the pre-vitamin cholecalciferol. It is this vitamin D that is found in egg yolks, oily fish, some fortified foods and some supplements.

Vitamin D2 can be found in supplements and comes from plant and/or fungal sources such as mushrooms.

So, vitamin D3 is the form naturally found in the body, and as a supplement is normally manufactured from lanolin which is sourced from sheep’s wool. Vegan supplements contain the D2 version of the vitamin.

That’s not the end of the story

Both vitamin D2 and vitamin D3 are converted by the liver to a third form of vitamin D, known as 25-hydroxyvitamin D, or 25(OH)D (calcidiol). This is still not the active form, but the form of vitamin D that can be measured by a blood test to calculate your levels. It has been scientifically shown that vitamin D3 increases levels of calcidiol more efficiently that vitamin D2(1).

It is the kidneys that convert 25-hydroxyvitamin D into its active form, 1,25 hydroxy vitamin D. This active form of vitamin D binds with the receptor on the genes to switch on different activities within the body. Vitamin D has been found to influence over 200 genes emphasising the importance of vitamin D for health.

Vitamin D supplements

If there are no issues for you taking a product derived from an animal source, always choose a vitamin D supplement that contains vitamin D in the D3 (cholecalciferol) form as this has been shown to be more efficient in being converted to its active form within the body.

If you are looking for a children’s vitamin D supplement try Haliborange children’s multivitamin Softies

Understanding the difference between D3 and D2 can greatly impact your overall health and wellbeing

Over the past year, we’ve all learnt to value our health more. And a big part of protecting your health and wellbeing involves ensuring that your immune system can function at full capacity.

This is where vitamin D comes in. Vitamin D is essential for bone, teeth and muscle health alike, and helps to promote healthy immune function. The majority of our vitamin D intake comes from sunlight, as well as foods like egg yolks, liver, oily fish and fatty spreads.[1]

Vitamin D doesn’t just refer to one single vitamin

We tend to think of vitamin D as just one vitamin, but in reality it’s a family of nutrients that all share a similar chemical structure. The most common members of this family are vitamin D2 and vitamin D3.[2]

Both of these types will help you meet your vitamin D requirements, but they differ in a few key ways. We’re going to take a closer look at what separates these two vitamin D products, and why vitamin D3 is so important.

Vitamin D3 vs. Vitamin D2

Both vitamins D2 and D3 are important for your immune health, but research suggests that vitamin D2 is less effective than vitamin D3 when it comes to raising blood levels of vitamin D.[3] Vitamin D is important for all of us at all times, but especially during the winter months, if you are inside a lot of the time, have darker skin or are an older adult.[4]

These two forms mainly differ in where they are sourced. Vitamin D3 tends to be found in animal-sourced foods, while D2 is mostly present in plant sources and fortified foods.

Some of the most common sources of vitamin D3 include oily fish, liver, butter and egg yolk, while vitamin D2 is mostly extracted from fungi. Because vitamin D2 is cheaper to produce, it’s the most common form of vitamin D in fortified foods.

Vitamin D3 is formed on the skin when exposed to sunlight. UVB radiation tiggers the formation of vitamin D3 from the compound 7-dehydrocholesterol.[5] This means that, for people in equatorial countries like India, an estimated half an hour of midday sun twice a week provides enough vitamin D3. However, in cooler countries like the UK, supplements can help us reach our RDA.

Why is vitamin D3 so important?

Vitamin D3 yields higher levels of calcifediol when compared to vitamin D2. Calcifediol is the main circulating form of vitamin D in the blood, and is how healthcare providers examine our vitamin D levels.

In a study of older women, vitamin D3 was found to be nearly twice as effective as vitamin D2 when it came to raising blood levels of calcifediol.[6] Vitamin D2 supplements are also thought to degrade more over time, as they are more sensitive to humidity and temperature changes.[7]

So when it comes to supporting your immune health, vitamin D3 is the best option.

Doctor Seaweed’s Weed & Wonderful® Immunity+ capsules provide a vegan source of vitamin D3

Despite the fact that vitamin D3 usually comes from animal sources like eggs and butter, our Immunity+ capsules use vitamin D3 extracted from lichens – an incredible symbiotic relationship between fungi and algae or cyanobacteria. This makes Immunity+ a wholly vegan source of vitamin D3, as well as providing both vitamin B12 and the benefits of seaweed.

All of this allows our Immunity+ capsules to contribute to numerous health benefits, including immune system function, thyroid health, metabolism, cognitive function and muscle function, as well as reducing tiredness and fatigue.

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References: [1] https://www.nhs.uk/conditions/vitamins-and-minerals/vitamin-d/ [2] https://www.nutraingredients.com/Article/2015/04/13/Vitamin-D2-vs-D3-Same-for-boosting-D-levels-but-D3-superior-for-sustaining-levels [3] https://academic.oup.com/jcem/article/89/11/5387/2844259 [4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399494/ [5] https://www.ncbi.nlm.nih.gov/pubmed/24067388 [6] https://www.ncbi.nlm.nih.gov/pubmed/18492750 [7] https://www.ncbi.nlm.nih.gov/pubmed/17023693

Why do doctors prescribe vitamin D2 instead of D3?

Vitamin D supplements are available as vitamin D2 (D2) and vitamin D3 (D3). Both versions can be used to treat vitamin D deficiency, but D3 seems to be more effective than D2. Vitamin D2 is still prescribed to people with low vitamin D levels, because it's more readily available in higher doses.

Which is better vitamin D2 or D3?

Studies have repeatedly shown that vitamin D3 is superior at raising levels of vitamin D in the body. These findings were supported by a recent review of the evidence which found that vitamin D3 supplementation increased vitamin D levels in the body better than vitamin D2.

Are vitamin D2 and vitamin D3 the same?

The two forms of vitamin D differ depending on their food sources. Vitamin D3 is only found in animal-sourced foods, whereas D2 mainly comes from plant sources and fortified foods. Since vitamin D2 is cheaper to produce, it's the most common form in fortified foods.

Do you need both vitamin D2 and D3?

Although you can safely take both vitamin D2 and D3 supplements, the effectiveness of the two forms of the vitamin differs. Experts agree that vitamin D3 is a preferable choice over D2. Not only is D3 the form that occurs naturally in the human body but it also raises blood levels of vitamin D much more effectively.